Osteoarthritis is a condition that causes cartilage (material providing padding ... While gout can affect any joint, it commonly affects the big toe. Symptoms of gout come and go. During flare-ups, ...

"Osteoarthritis will typically manifest in the great toe joint, midfoot, or ankle, but it can be seen in any joint in the foot," says Dr. Alissa Kuizinas, a Massachusetts-based podiatrist.