As Dbp5 shuttles, it could interact with Yra1 within the nucleus. The final steps in mRNA export consist of removing proteins from the mRNP and transferring the mRNA to the translation machinery.

In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide ...

It is titled "Genome organization around nuclear speckles drives mRNA splicing efficiency." For a decade, researchers in the Guttman laboratory have studied how the nucleus is spatially organized ...

据企业官网，唐定国也是斯微生物的联合创始人。2020年初，新冠疫情危机骤起，mRNA领域的投资热情随之爆发，李航文的创业公司便开启了疾速发展 ...

The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.

Researchers demonstrated that several findings in Alzheimer's disease are observed across disorders, identifying potential ...

Moderna uses the same mRNA technology in its highly safe and effective coronavirus vaccine. In the study, six macaques were vaccinated with the mRNA vaccine, and another six received an equivalent ...

After an initial defeat against the biggest barrier to mRNA flu vaccines—namely, B strains of influenza—GSK has returned with a reformulated candidate that has delivered the goods in the all ...

A new vaccine candidate from Moderna, mRNA-1769, more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a ...

Is MRNA stock a sell? Moderna (MRNA) reachead $63.94 at the closing of the latest trading day, reflecting a -0.31% change compared to its last close. The most oversold stocks in the health care ...

The investigational mRNA cancer immunotherapy is targeted for patients with lung cancer, melanoma and other solid tumours. Nineteen patients with advanced stage cancers received between one and ...

A new vaccine candidate from Moderna, mRNA-1769, more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a ...