“It would teach the immune system that the myelin basic protein is not a foreign substance,” says Catz. In 1997, the researchers launched a two-year, placebo-controlled phase 2 clinical trial ...
They found that mice expressing a transgenic CD8 + T cell receptor specific for myelin basic protein developed multiple sclerosis–like disease after infection with a vaccinia virus. This onset ...
immunochemical features of myelin basic protein, and the relationship of myelin basic protein-like material and para-cresol sulfate. New programs of research are in the areas of delayed myelinogenesis ...