Isolated complex I deficiency was detected in muscle tissue and cultured fibroblasts. The boys died at 14 and 17 months from aspiration pneumonia 10. Neither cranial MRIs nor post-mortem reports ...

Pollak, Michael N. Papkovsky, Dmitri B. and Topisirovic, Ivan 2022. Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have made a major discovery in how human ...