5,10-Methylenetetrahydrofolate reductase ... TGF-β1, or 5,10-MTHFR gene polymorphisms and the risk of BPD. There are a few possible explanations for our negative results. We can speculate ...
A total of 124 RA patients, 101 (81.5%) women and 23 (18.5%) men, treated with MTX in monotherapy, were enrolled in this study. They had taken 0–3 DMARDs prior to treatment with MTX. Ninety-five ...
Polymorphisms in genes encoding proteins in two major cellular pathways influenced by MTX, namely the folate and adenosine pathways, and their association with response to MTX have been examined ...
Inborn errors of metabolism (IEMs) are genetic disorders characterized by dysfunction of an enzyme or other protein involved in cellular metabolism. In most cases, IEMs involve the nervous system.
It illustrates balanced polymorphism because carriers are resistant to malaria, an infection by the parasite Plasmodium falciparum that causes cycles of chills and fever. The parasite spends the ...
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