乳腺癌是美国女性癌症相关死亡的第二大原因，每年报告的新病例超过30万，42,250人死亡。获得转移表型约占BC相关死亡的90%。转移性BC通常无法治愈，受累患者的中位生存期只有1.5 ~ ...

【导读】Kindlin-2是一种衔接蛋白，在多种人类癌症中失调，包括三阴性乳腺癌(TNBC)，它通过影响几种癌症标志来驱动肿瘤进展和转移。9月19日，美国凯斯西储大学研究学者在期刊《Oncogene》上发表了研究论文，题为“Kindlin-2 ...

【导读】癌症是一种涉及复杂分子网络的全身性异质性疾病。肿瘤的形成涉及上皮-间充质转化 (EMT)， ...

2006) given the recent finding that expression of Gli2 in MDA-MB-231 cells mediates osteolytic behavior of these cells via induction of parathyroid hormone-related protein. Other than these studies, ...

The apoptotic response was more pronounced in MCF-7 cells than in MDA-MB-231 cells, indicating a selective action of MH on ER ...

the research team conducted a series of experiments in mice and in ER-positive MCF-7 and triple-negative MDA-MB-231 breast ...

Gr3-MB is one of the most ... July 8, 2024 — Researchers have discovered a new potential drug target for the lethal wasting disease known as cancer cachexia. Their findings illustrate that even ...

Tumors are one of the most misunderstood diagnoses or conditions. While no one wants to be told they have one, many people don't realize that a tumor is nothing more than a clump of abnormal cells ...

A new research paper was published in Oncotarget, titled "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties." As stated within the paper, despite ...

Future Oncol. 2010;6(1):55-74. Stimulates proliferation, migration and invasiveness of breast cancer cells SPRYCEL Phase III trials recruiting for CML Phase I/II (+ZA) recruit Important for proper ...