乳腺癌是美国女性癌症相关死亡的第二大原因，每年报告的新病例超过30万，42,250人死亡。获得转移表型约占BC相关死亡的90%。转移性BC通常无法治愈，受累患者的中位生存期只有1.5 ~ ...

【导读】Kindlin-2是一种衔接蛋白，在多种人类癌症中失调，包括三阴性乳腺癌(TNBC)，它通过影响几种癌症标志来驱动肿瘤进展和转移。9月19日，美国凯斯西储大学研究学者在期刊《Oncogene》上发表了研究论文，题为“Kindlin-2 ...

【导读】癌症是一种涉及复杂分子网络的全身性异质性疾病。肿瘤的形成涉及上皮-间充质转化 (EMT)， ...

2006) given the recent finding that expression of Gli2 in MDA-MB-231 cells mediates osteolytic behavior of these cells via induction of parathyroid hormone-related protein. Other than these studies, ...

The apoptotic response was more pronounced in MCF-7 cells than in MDA-MB-231 cells, indicating a selective action of MH on ER ...

the research team conducted a series of experiments in mice and in ER-positive MCF-7 and triple-negative MDA-MB-231 breast ...

13, 2024 — A drug that delivers chemotherapy directly to tumors has shown impressive activity ... and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain. Gr3-MB is one of the ...

Tumors are one of the most misunderstood diagnoses or conditions. While no one wants to be told they have one, many people don't realize that a tumor is nothing more than a clump of abnormal cells ...

A new research paper was published in Oncotarget, titled "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties." As stated within the paper, despite ...

Future Oncol. 2010;6(1):55-74. Stimulates proliferation, migration and invasiveness of breast cancer cells SPRYCEL Phase III trials recruiting for CML Phase I/II (+ZA) recruit Important for proper ...