Liver epithelial cell lines are considered the cell culture counterpart of liver stem/progenitor cells (for a detailed review, see Grisham and Thorgeirsson [10]). Several laboratories, including ...

Sodium butyrate modulates necroptosis in intestinal epithelial cells during liver cirrhosis, offering potential therapeutic ...

Necroptosis is critical for regulating intestinal epithelial cells (IECs). Butyric acid (BA), produced during intestinal ...

These observations have resulted in the hypothesis that bone marrow resident stem cells, specifically HSCs, are an important source for liver epithelial cell replacement, particularly during ...

Bile ducts are pathways that carry hepatocyte-produced bile from the liver to the small intestine. In the human fetal liver, bile ducts are formed from bile duct epithelial cells surrounding the ...

which include a population of liver epithelial progenitors that can give rise to organoids capable of developing into hepatocytes or bile duct cells.

PMID: 39393543). We are also interested in understanding the development of inflammatory bowel diseases, with a focus on identifying key disease-driving pathways in immune and epithelial cells in the ...