The team also used a special kind of light to check the amount of a pigment called lipofuscin, which increases as worms get older. After treating the worms with doxycycline for 13 days, they found ...

“These are devastating diseases with limited treatment options,” said Curt Breneman, Ph.D., dean of Rensselaer’s School of ...

They received a $6.4 million grant to support drug development and IND-enabling toxicology studies. Bispecific drugs act as ...

It is characterized by lipofuscin accumulation in the retina. Stargardt disease is a rare genetic eye disease in which vision loss typically begins in childhood. In Stargardt macular degeneration ...

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...

The condition gets its name from the distinctive pigmentation that occurs in the colon's lining due to the accumulation of a pigment known as lipofuscin. While melanosis coli is typically harmless ...

Syndromic eye diseases are complex disorders of ophthalmologic interest in which the involvement of the eye is but one of the cardinal features of the disease. There are myriad syndromic eye ...

Determined the high dose of OCU410ST to be the maximum tolerated doseNo serious adverse events have been reportedApproved proceeding to Phase 2 using high and medium doses of OCU410ST MALVERN, Pa., ...