it will take no more than a few milliseconds for the postsynaptic ligand-gated channels to open and trigger a cascade of electrochemical signaling pathways. Information transmitted by synaptic ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

The predicted membrane topology showed a long extracellular N terminal that presumably constitutes the ligand binding site. Homology with the Ca 2+ receptor CaSR of the parathyroid, with ...

It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ...

Several key molecules have been characterized, including the permethrin-sensitive sodium channel gene, an ivermectin sensitive ligand-gated chloride channel, and several ABC transporter genes and ...

The receptor is one found in the mouths and brains of silk moths. As a ligand-gated receptor, it becomes activated only after its ligand—the molecule that's able to bind to it—attaches. Unexpectedly, ...

The silk moth’s mouth and brain contain the receptor. Because it is a ligand-gated receptor, activation occurs only in response to the ligand the molecule that is able to bind to it attaches.

秋风送爽，丹桂飘香。近日（9月19日-22日），由中华医学会、中华医学会神经病学分会主办，河南省医学会承办的“中华医学会第二十七次神经病学学术会议”在美丽的郑州顺利召开。国内外知名专家学者齐聚，共享学术饕餮盛宴。神经病理性疼痛（NP）指由躯体感觉系统 ...

It can be used for a wide range of analyses, including kinetic analysis, titers IgG and other proteins, reagent quantification, crude antibody screening, epitope binning/mapping, ligand binding assays ...

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of ...