The following is a summary of "Comparison of first-line chemotherapy regimens in unresectable locally advanced or metastatic ...

Chemotherapy for three months demonstrates lower side effects, suggesting its use as standard care compared with six months.

Leucovorin is commonly used to reduce toxicity ... commonly used to prevent seizures 5-fluorouracil (5-FU), which is a chemotherapy that is used to treat certain cancers Sulfamethoxazole ...

The majority of patients received 12 cycles of protocol-specific chemotherapy (74.7% received FOLFOX4 and 86.5% received 5-fluorouracil plus leucovorin). In addition, most patients whose disease ...

Leucovorin; mCRC: Metastatic colorectal cancer; RT: Radiotherapy. Toxicity ≥3 or ≥2 according to CTCAE v2.0 Decreased risk of toxicity for the haplotype 677C-1298C in 5-FU + RT-treated ...

The single-arm (only one treatment type or regimen) Phase II trial evaluated a modified form of the chemotherapy treatment FOLFIRINOX (a combination treatment consisting of leucovorin calcium ...

The U.S. Food and Drug Administration has approved Vyloy (zolbetuximab-clzb) in combination with fluoropyrimidine- and ...

Both the SPOTLIGHT study (Vyloy plus the combination of mFOLFOX6 chemotherapy regimen of oxaliplatin, leucovorin, and fluorouracil versus placebo plus mFOLFOX6) and the GLOW study (Vyloy plus the ...

CET: Cetuximab; Chrono-IFLO: Chronomodulated 5fluorouracil/leucovorin, oxaliplatin and irinotecan; FLOX: bolus 5fluorouracil/leucovorin and oxaliplatin; FOLFIRI ...

Methotrexate sodium, a chemotherapy drug used for leukemia, brain tumors and non-Hodgkin lymphoma, is among the pediatric cancer drugs most commonly in shortage. Leucovorin, used to treat the side ...