PTC Therapeutics' Kebilidi gains FDA accelerated approval as the first brain-administered gene therapy in the U.S. for AADC ...

This bodily hypotonia affected and weakened Paul's ear muscles and auditory zoom, so it couldn't differentiate the frequencies of human speech. (Our auditory zoom allows us, when we enter a ...

severe muscle hypotonia at birth, scoliosis at birth, scleral fragility, rupture of the ocular globe • Positive family history (e.g., affected siblings) • Physical findings include tissue ...

Agbayani said his daughter had cerebral palsy, epilepsy, hypotonia and chronic lung disease, and often had to have secretions ...

Many affected children also have microcephaly (small head), axial hypotonia (decreased muscle tone), and appendicular hypertonia with spasticity on neurological examination. We see additional eye ...

Speech and language development: Delayed speech and language acquisition, often requiring speech therapy. Low Muscle Tone (Hypotonia): Babies with Down syndrome may have reduced muscle tone, which can ...

Mechanical ventilation was required for 6 days. In addition, the infant exhibited pronounced muscular hypotonia (“floppy infant”) and very poor feeding, with prolonged weaning from tube ...

At the age of five months, the children presented with repeated vomiting and developed strabismus, progressive muscular hypotonia, myoclonic epilepsy and psychomotor regression. A cranial CT-scan ...

Fetal/Neonatal Adverse Reactions: May cause respiratory depression, hypotonia, and sedation in neonates. Monitor neonates exposed to Klonopin during pregnancy or labor for signs of sedation ...