It acquired rights to taligurase alfa, a form of the enzyme glucocerebrosidase in development for the treatment of Gaucher's disease, from Protalix Biotherapeutics in Carmiel, Israel. Protalix has ...

As per the National Gaucher Foundation, this disease was first discovered by a French doctor, Philippe Gaucher, after whom it ...

New Delhi: Reviewing the Phase III clinical trial protocol of the GZ402671 (Venglustat) presented by the pharma major Sanofi, ...

The purpose of this study was to investigate the safety and efficacy of recombinant human GAA (rhGAA) enzyme therapy for this fatal disorder. Methods: The study was designed as a phase I/II ...

This causes the formation of more enzyme-substrate complexes, leading to an increase in enzyme activity. This means the active site loses its important shape and can no longer form enzyme ...

How does your body speed up these important reactions? The answer is enzymes. Enzymes in our bodies are catalysts that speed up reactions by helping to lower the activation energy needed to start a ...

"We assume that the improved stability of the enzyme enables it to evade being ... Efficacy of an AAV vector encoding a thermostable form of glucocerebrosidase in alleviating symptoms in a Gaucher ...

pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

The PINK1 gene instructs the body to make a protein kinase (an enzyme) that protects the ... linked Parkinson’s with low activity in the glucocerebrosidase beta (GBA1) gene, which tells the ...

Biologists at Washington University in St. Louis have discovered the origin of a curious duplication that gives plants multiple ways to override instructions that are coded into their DNA. This ...

After which I worked in the Neurology department at the University Hospital Dresden as a research associate on an EU funded project investigating Co-enzyme Q deficiency in patient tissue. I joined the ...