First human trial of stem-cell-derived corneal transplants for LSCD shows vision improvement, suggesting a safe and effective ...

Researchers led by Osaka University in Japan have conducted the first human trial using induced pluripotent stem-cell-derived ...

This scar tissue, called fibrotic encapsulation, is the body's attempt to protect itself from foreign objects, but it often leads to implant failure by blocking the device's function. By studying ...

The fibrotic and destructive nature of this lesion ... The lesion also occurs from certain types of toxic fumes, some of the connective tissue diseases, specific types of medications and post ...

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

CUR influences cellular autophagy, by supporting tissue homeostasis and limiting fibrosis progression. In fibrosis models, CUR enhances autophagy, effectively manages fibrotic lesions, and ...

The EFTISARC-NEO trial, with a data cut-off of 20 October 2024, also showed 71.4% of patients achieved a pathologic response ...