Studies on how endothelial 'tip, stalk and phalanx cells' form sprouts have identified promising candidate targets with complementary mechanisms to VEGF. This Review provides a conceptual ...
The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ensues. This pathway is evolutionarily conserved and is obligate for ...
Here I developed a platform for functional screening of flow-responsive apoptotic regulators in zebrafish. I subsequently used this model to identify mechanoreceptors regulating endothelial apoptosis ...
Signals triggering a type of cell suicide called apoptosis move through a cell like a wave, traveling at a rate of 30 micrometers per minute, Stanford University systems biologists Xianrui Cheng ...
Atherosclerosis involves multiple processes including endothelial dysfunction ... to other cellular processes such as inflammation, apoptosis and matrix alterations. The contribution of vascular ...
Doxazosin remains a commonly used antihypertensive medication, although its use has been tainted by recent findings from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack ...
The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ensues. This pathway is evolutionarily conserved ... Gemcitabine kills ...
Live-cell microscopy routinely provides massive amount of time-lapse images of complex cellular systems under various physiological or therapeutic conditions. However, this wealth of data remains ...