An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy ...

【导读】结直肠癌(CRC)中错误折叠蛋白的长期积累导致内质网(ER)应激。然而，控制结直肠癌存活和凋亡的确切通路尚不清楚。 9月13日，南京医科大学傅赞研究团队在期刊《Journal of Experimental & Clinical Cancer ...

An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy ...

本文发表后，一位热心的读者向编辑指出，第3763页图1D中显示的某些细胞凋亡测定数据，与另一篇由不同研究机构的不同作者以不同形式提交发表的文章（图3A）中的数据惊人地相似。鉴于上述有争议的数据在提交给《 Molecular Medicine ...

A research team from Osaka University has discovered a novel mechanism essential for initiating autophagy. The study ...

A detailed quantitative model of signaling by IRE1 sheds light on the mechanism of its activation by endoplasmic reticulum stress and addresses a long-standing controversy in the field. In ...

Irrational antibiotic use damages mucus barrier, leading to intestinal inflammation, as shown in recent Science Advances ...

Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...

Researchers at University of Tsukuba have meticulously examined the gametogenesis of budding yeast, a process involving ...

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the ...