Both the ectodomain and the first extracellular loop of another class B peptide hormone receptor, the glucagon receptor, are important for agonist binding and potency 7.

Xu K, Tzvetkova-Robev D, Xu Y, Goldgur Y, Chan YP, Himanen JP, Nikolov DB., Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ...

Xu K, Tzvetkova-Robev D, Xu Y, Goldgur Y, Chan YP, Himanen JP, Nikolov DB. (2013). Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...