该研究通过简易的蛋白质改造策略，利用TadA同源物开发靶向范围更广的胞嘧啶碱基编辑器，并首次在DMD小鼠模型中实现了外显子55的跳跃。 碱基编辑（Base editing，BE）可以实现单个碱基的精准编辑，被认为是更安全的基因编辑方式，在基础研究、药物开发、基因 ...

A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular ...

Fruits and vegetables, as a type of food, are characterized by the presence of health-beneficial components, such as dietary ...

V. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its ...