One strong strategy is to use a culture system. Coculture of dorsal root ganglion neurons and Schwann cells can promote efficient myelin formation in vitro (Figure 1E). Researchers can modify the ...

The axon is surrounded by multilamellar structure of myelin. (E) Myelinated nerve fiber reproduced in vitro by coculture of rat dorsal root ganglion neurons and Schwann cells. Myelin segments are ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The gut microbiota and its functional metabolites play crucial roles in the development of intestinal fibrosis in patients ...