Chromatin structure describes the physical structure of chromatin within the eukaryotic nucleus and how structure affects chromatin processes such as transcription. The repeating unit of chromatin ...

The Mattiroli group's researchers discovered that the speed at which DNA is replicated during cell division can be directly ...

Therefore, chromatin is further coiled into an even ... Thus, the 30-nanometer fiber may be highly irregular and not quite the uniform structure depicted in instructive drawings such as Figure ...

Researchers have identified a key weakness in acute myeloid leukemia, offering a promising new strategy to delay the ...

A study described the three-dimensional architecture of turtle genomes, which fold in a configuration unlike any other animal observed so far.

The proper folding of the chromatin structure plays a crucial role in the regulation of genomic DNA functions, its disruption leading to various diseases. Therefore, understanding the chromatin ...

In a recent paper published in the journal Genome Research, experts described the chromatin arrangement in the genomes of two ...

Researchers have identified a key weakness in acute myeloid leukaemia, offering a promising new strategy to delay the ...

How and where the chromatin fiber folds and loops onto itself affects what genes are activated. Findings from an Iowa State ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

研究者在一种参与脂肪醛氧化的酶附近发现了一种假定的因果变异，并在酵母中测试了这种基因，以确认其产生色素变化的能力。研究中广泛的生化和遗传学工作有助于人们了解非模式生物的颜色，为未来对鹦鹉和其他鸟类色素沉着的研究打开大门。

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...