Bile acids are byproducts of cholesterol metabolism in the liver and constitute the primary components of bile. Disruption of ...

FIC1 disease collectively refers to a group of autosomal-recessive familial liver disorders characterized by intrahepatic cholestasis due to mutations in the ATP8B1 gene (initially named FIC1).

This study examined the natural history of infants born with alpha-1 antitrypsin (AAT) deficiency and liver disease ... by too few bile ducts resulting in cholestasis, can damage not only the ...

European Commission grants conditional marketing authorization for Iqirvo® (elafibranor), first-in-class new treatment for primary biliary ...

Drug-induced liver injury including cholestasis is another form of acquired liver disease, accounting for approximately 2 to 5% of hospitalizations for jaundice, 10% of cases of hepatitis in all ...

Sokol M.D. When first encountering an infant or child with cholestatic liver disease, it is essential that diagnostic evaluation be conducted promptly in order to (i) recognize disorders amenable ...

genetic mutations Cholestatic liver diseases Decompensated hypothyroidism Nephrotic syndrome, chronic kidney disease Cushing's syndrome Psychological anorexia Medications' side effects (progestin, ...

Seventeen consortium centers collected data during the study period, focusing on pediatric liver diseases and aiming to describe the natural history and genetic and environmental modifiers of a group ...

Texas Children's Liver Center, Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children's Hospital, Houston, Texas With the recent findings of genetic causes of cholestasis ...