A new bioprocessing technique developed by a team of researchers could improve a range of therapies based on CAR-T cells.
Researchers discover a novel protein therapy that recharges exhausted T cells, unleashing their power to eradicate tumors and ...
During a Case-Based Roundtable® event, Matthew A. Lunning, DO, discussed the updated trial data for 2 chimeric antigen ...
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune ...
"Hot tumors tend to have a greater number of lymphocytes, in particular T cells, certainly CD8 but probably also CD4, cells that are specific for ... impact on cancer immunotherapy in the near future.
An arist's illustration of DeltaRex-G mechanism of action in CAR-T induced CRS. By killing a certain proportion ... supported by the inhibitory activity of DeltaRex-G in transduced CD4+ CD8+ cell ...
CAR-T细胞在血液瘤中的成功尚未转化为实体肿瘤 ... 共享新抗原和个体化新抗原）、非突变共享抗原的相对作用，以及在这种情况下CD4+ T细胞和CD8+ T细胞的激活作用，各种问题仍然存在。
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