Activation of T cells by antigen ... and T-cell effector functions. Now, Chan and colleagues describe a previously unrecognized late phase of cell polarity in some CD4 + T cells that is controlled ...

Ovarian tumors are infiltrated by both effector (CD4+CD25-) T cells and by an excess of TREG cells (CD4+CD25+). These TREG cells impede the function of the effectors in combating the tumor.

New research shows that blood-based immunophenotyping can enhance rheumatoid arthritis treatment by identifying immune ...