Review the side-effects of Boceprevir as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of ...

We performed the design and characterization of three covalent hybrid inhibitors BBH-1, BBH-2 and NBH-2 created by splicing components of hepatitis C protease inhibitors boceprevir and narlaprevir, ...

Both the boceprevir and telaprevir phase III studies used the COBAS TaqMan HCV RNA assay, version 2.0 (Roche), with a LLOD of 10 IU/mL and a LLOQ of 25 IU/mL. Eligibility for RGT was based on the ...

Using a single medication alone can lead to drug resistance. Most DAAs are only available as part of a combination pill. The first-generation hepatitis C protease inhibitors, boceprevir (Victrelis) ...

Most of the antiviral agents that have been approved, and are currently used in the treatment of virus infections, are targeted at HIV, HBV, herpes simplex virus (HSV), varicella-zoster virus (VZV ...

Ruxolitinib is a kinase inhibitor, prescribed for high-risk myelofibrosis. The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Bacillus calmette-guerin ...

Amy Dounay '96 returned to Colorado College as an assistant professor in the Department of Chemistry and Biochemistry in 2012. She obtained her Ph.D. in organic chemistry at the University of ...

Hepatitis C is liver inflammation and damage caused by infection with the hepatitis C virus. Hep C can cause a mild illness that lasts a short time (acute) or a serious illness that can last the ...