People of Ashkenazi Jewish descent are at higher risk of developing pancreatic cancer because they are more likely than other ...

Sung received the award for his work on the mechanisms behind homology-directed repair, a DNA repair mechanism that can be ...

Carriers of BRCA2 mutants have a similar risk of breast cancer and a more moderately increased risk of ovarian cancer. BRCA1 and BRCA2, located on the long arms of chromosomes 17 and 13 ...

BRCA1 and BRCA2 are some of the most well-known cancer mutations, but others include APC, ATM, CHEK2, PALB2 and more. Being a previvor often means visiting the doctor a lot more than normal ...

Breast cancer, though rare in men, poses real risks linked to genetic and environmental factors. Early detection through ...

Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...

For more than a decade, Ruth has written for multiple outlets providing patient education, including Health and Verywell. She has written for health student education companies, collaborating on ...

Understanding genetic risks and identifying BRCA1 and BRCA2 mutations can guide preventive and personalised treatment strategies for patients at high risk of hereditary breast cancer.

This was a huge step forward, but the statistics suggested that there was a significant amount of hereditary breast cancer not linked to the BRCA1 gene and the search for a second breast cancer gene ...

More specifically, they will educate others about BRCA variants — a harmful change in the BRCA1 or BRCA2 genes — and how these increase one’s chances of developing breast, ovarian ...

前列腺癌是一种具有高度遗传性的癌症，据估计约40%～50%的前列腺癌与遗传因素相关。流行病学和家系研究证实前列腺癌有明显的家族聚集性，在这些家族性前列腺癌中，遗传因素扮演了尤为重要的角色。目前已证实多个DNA损伤修复基因的胚系突变与前列腺癌遗传易感相关。以BRCA1和BRCA2为代表的DNA损伤修复基因是迄今为止认识最充 ...