Rheumatologists see the greatest potential in anti-B-cell activating factor (BAFF-R) inhibitors, such as Novartis’ ianalumab, for managing Sjögren’s disease. Other promising MOAs attracting ...

Ianalumab (previously known as VAY736) is a novel BAFF-targeting antibody that was recently evaluated in patients with pSS.

【导读】为了解决免疫逃逸问题，多特异性CAR-T细胞策略使用能够特异性结合恶性细胞上多个受体的天然配体。在这种情况下，团队提出了一种分体CAR设计，包括在T细胞上表达的通用受体和基于配体的开关分子，这种设计保留了像APRIL和BAFF这样的配体的天然 ...

A quick response and teamwork were credited with saving a $1 million home near Bartlett Village on Monday night. Firefighters ...

It has broadened its R&D focus in recent years to include protein ... They note that competition in IgAN will be fierce, as several BAFF and/or APRIL inhibitors could launch ahead of povetacicept ...

Here is a list of matters listed at Port Macquarie Local Court on Wednesday. Today's court listings are published as part of News Corporation's commitment to public interest journalism and are ...

Vertex Pharmaceuticals Incorporated VRTX reported adjusted earnings of $4.38 per share for the third quarter of 2024, ...

[{"search_type":"general-inventory-search","vehicle_array":[{"trim":"Summit","make":"Jeep","cat":"suv_midsize","year":"2018","customer_id":"179274","listing_id ...

Presented positive 96-week long-term eGFR stabilization data from ORIGIN Ph 2b clinical trial of atacicept in IgAN in a late-breaking oral ...

We announced that the first participant has been dosed in a Phase I study of AUR200, our BAFF/APRIL dual antagonist for ...