Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable ...

A Vero-cell-culture–derived trivalent influenza vaccine had a protective efficacy of 79% against antigenically matched influenza strains. Conventional egg-based influenza vaccines have several ...

This technology employs protein engineering to stabilize S in its prefusion conformation, preventing structural rearrangement, and exposing antigenically preferable surfaces. The technology has ...