In most cases, both alleles are transcribed; this is known as bi-allelic expression (left). However, a minority of genes show monoallelic expression (right). In these cases, only one allele of a ...
Annual Meeting, the leaders in clinical polygenic risk score (PRS) analysis at Allelica unveiled a groundbreaking approach to modeling human genetic diversity without predefined labels. This new ...
“Novel allelic variation is illustrative of the power of pangenomics”, emphasises Prof. Dr. Nils Stein, head of IPK’s department “Genebank”. “Our findings indicate that much of the allelic diversity ...
An allelic series of miR-17~92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron. Nat Genet. 2015 Jun 1. doi: 10.1038/ng.3321. [Epub ahead of print ...