The allele frequency represents the incidence of a gene variant in a population. Alleles are variant forms of a gene that are located at the same position, or genetic locus, on a chromosome.
让人意外的发现是,IgG1-G396R变异体在全球人口中出现显著两极化分布态势,其在非洲、欧洲、美洲(含北美洲,中美洲和南美洲)和大洋洲的主体人口中出现频率极低(minor allele frequency,MAF,仅为万分之几),但是在如下族群人口中频率较高:Bougainville population ...
The developed statistical method paves the way for next generation demographic and selection inference by combining information from several heritable genomic and epigenomic markers.