The analysis included hormone receptor and HER2/neu status to define subtypes: HR+ HER2+, HR+ HER2−, HR− HER2+, and HR− HER2− ...

During a Case-Based Roundtable® event, Michael J. Birrer, MD, PhD, moderated a discussion on what factors affect the need for ...

The US Food and Drug Administration (FDA) has approved a 420 mg dosage strength of Hercessi (trastuzumab-strf), a biosimilar to Herceptin (trastuzumab). Hercessi, a HER2/neu receptor antagonist, is ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

Included studies compared survival between Black and White female patients with breast cancer within subtypes defined by hormone receptor and human epidermal growth factor receptor 2 (HER2)/neu (HER2; ...

The Food and Drug Administration (FDA) has just approved the drug Kisqali (ribociclib) in combination with an aromatase ...

The potential to treat GEA by targeting HER2 was confirmed in 2010 when researchers showed that adding Roche’s Herceptin to chemotherapy extended OS from 11.1 months to 13.8 months.

Foods such as sugar, saturated fats, and alcohol may promote the spread of HER2-positive breast cancer and should be avoided if you have this cancer. Some other foods may slow the cancer’s progress.

What Is HER2-Positive Breast Cancer? HER2-positive breast cancer is when breast cancer cells have a protein receptor called human epidermal growth factor receptor 2 (HER2). Normally, this protein ...

A review of HER2 overexpression and somatic mutations in cancers, Critical Reviews in Oncology/Hematology, Volume 186, 2023, 103997 14 Wilding, B et al. Cancer Discov. 2024. DOI 10.1158/2159-8290 ...

Caption The traditional HER2 score evaluation depends on manual inspection of tissue slides by pathologists. Our presented methodology introduces automated HER2 scoring using pyramid sampling and ...

Subtypes of breast cancer are also based on whether the cancer cells have hormone receptors or human epidermal growth factor 2 (HER2) receptors. Photo composite by Joules Garcia for Verywell Health; ...