Reperfusion injury - Wikipedia
网页Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re- + perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
Vascular Reperfusion Injury - StatPearls - NCBI Bookshelf
网页2023年8月14日 · Once reperfusion injury has occurred, it can present as acute heart failure, cerebral dysfunction, SIRS (systemic inflammatory response system), and multi-organ failure. The most common presentation of reperfusion in the heart is ventricular arrhythmias, myocardial wall rupture, microvasculature abnormalities, and myocyte death.
REPERFUSION中文(简体)翻译：剑桥词典 - Cambridge Dictionary
网页the action of making blood flow return to normal after the supply has been cut off, especially after a heart attack or stroke. （尤指在心脏病发作或中风之后使血液循环恢复正常的）再 …
Pathophysiology of Reperfusion Injury - Mechanisms of …
网页Reperfusion injury is a multi-factorial process resulting in extensive tissue destruction. The aim of this review is to summarise these molecular and cellular mechanisms and thus provide an insight into possible windows for effective therapeutic intervention.
Approach to reperfusion therapy for acute ischemic stroke
网页2024年8月7日 · The immediate goal of reperfusion therapy for acute ischemic stroke is to restore blood flow to the regions of brain that are ischemic but not yet infarcted. The long-term goal is to improve outcome by reducing stroke-related disability and mortality.
Ischemia and reperfusion—from mechanism to translation
网页2011年11月7日 · Ischemia and reperfusion is a pathological condition characterized by an initial restriction of blood supply to an organ followed by the subsequent restoration of perfusion and concomitant...
Reperfusion injury of the heart - UpToDate
网页2023年11月14日 · INTRODUCTION. Myocardial injury in the setting of an acute myocardial infarction (MI) is the result of ischemic and reperfusion injury. Reperfusion therapies, including primary percutaneous coronary intervention and fibrinolytic therapy, promptly restore blood flow to ischemic myocardium and limit infarct size.
Reperfusion Therapies for Acute Ischemic Stroke | Stroke
网页2010年12月16日 · There are still several challenges in the near future of reperfusion therapy for acute ischemic stroke, such as improving the ultra-early access to treatment within the “golden hour,” extending the therapeutic window beyond the current 4.5-hour time window, and developing novel thrombolitics or combined approaches to improve treatment ...
Ischemia/Reperfusion Injury: Pathophysiology, Current Clinical ...
网页2020年1月29日 · Abstract. Myocardial ischemia reperfusion syndrome is a complex entity where many inflammatory mediators play different roles, both to enhance myocardial infarction-derived damage and to heal injury.
Ischemia-reperfusion injury: molecular mechanisms and …
网页2024年1月8日 · Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate mechanisms...