Intrapleural pressure - Wikipedia
网页In physiology, intrapleural pressure refers to the pressure within the pleural cavity. Normally, the pressure within the pleural cavity is slightly less than the atmospheric pressure, which is known as negative pressure. [1]
Intrapleural Use of Tissue Plasminogen Activator and DNase in …
网页2011年8月11日 · Intrapleural t-PA–DNase therapy improved fluid drainage in patients with pleural infection and reduced the frequency of surgical referral and the duration of the hospital stay.
Intrapleural Catheter - StatPearls - NCBI Bookshelf
网页2023年2月8日 · An intrapleural catheter (IPC) is the treatment of choice for MPEs associated with respiratory failure. Lung cancer is the most common cause of MPEs, followed by breast cancer and lymphoma. Non Malignant Pleural Effusions
Recent Insights into the Management of Pleural Infection
网页2021年7月14日 · The key components of managing pleural infection are appropriate antimicrobial therapy and chest-tube drainage. In patients who fail medical therapy by manifesting persistent sepsis despite standard measures, surgical intervention to clear the infected space or intrapleural fibrinolytic therapy …
Management of Pleural Infection - PMC - National Center for ...
网页2020年12月9日 · Intrapleural antibiotic therapy has often been proposed as a way of overcoming the poor pleural penetrance seen with a number of antibiotic classes. A recent review found little evidence to support the routine use of these therapies in post-pneumonic pleural infection, although there is more evidence for its use in post-pneumonectomy infections ...
Intrapleural nano-immunotherapy promotes innate and …
网页2021年12月16日 · Here the authors design a liposomal nanoparticle loaded with cyclic dinucleotide for targeted activation of STING signalling in macrophages and dendritic cells and show that, on intrapleural ...
Intrapleural therapy - HUGGINS - 2011 - Wiley Online Library
网页2011年6月14日 · Numerous intrapleural therapies have been adopted to treat a vast array of pleural diseases. The first intrapleural therapies proposed focused on the use of fibrinolytics and DNase to promote fluid drainage in empyema.
Intrapleural Anticancer Therapy for Malignant Pleural Diseases: …
网页In this article, we aimed to review the management of primary pleural malignancy as well as malignant pleural effusion and assess the current state of intrapleural anticancer therapies. We review the role intrapleural chemotherapy, immunotherapy, and immunogene therapy, as well as oncolytic viral, therapy and intrapleural drug device combination.
Intrapleural immunotherapy: An update on emerging …
网页We have reviewed the literature to provide a comprehensive summary of novel intrapleural immunotherapeutic paradigms, including oncolytic virus therapy, gene-mediated cytotoxic immunotherapy, direct cytokine-mediated immunotherapies, innate immunomodulators and adoptive transfer of intrapleural chimeric antigen receptor T-cell therapy.
Intrapleural therapy - PubMed
网页Numerous intrapleural therapies have been adopted to treat a vast array of pleural diseases. The first intrapleural therapies proposed focused on the use of fibrinolytics and DNase to promote fluid drainage in empyema. Numerous case series and five randomized controlled trials have been published to ….