Enolase - Wikipedia
网页Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis.
Enolase: A Key Player in the Metabolism and a Probable …
网页2011年4月7日 · Enolase is the enzyme responsible for the reversible conversion of D-2-phosphoglycerate (2PGA) and phosphoenolpyruvate (PEP) in glycolysis and gluconeogenesis, two metabolic pathways that are often vital for cellular function . Enolase is a highly conserved protein found in Archaea, Bacteria, and eukaryotes with catalytic …
α-Enolase, a Multifunctional Protein: Its Role on …
网页2012年10月14日 · Enolase, also known as phosphopyruvate hydratase, was discovered in 1934 by Lohman and Mayerhof. It is one of the most abundantly expressed cytosolic proteins in many organisms.
Enolase 1, a Moonlighting Protein, as a Potential Target for …
网页2021年9月21日 · Enolase 1 (ENO1) is a moonlighting protein, function as a glycolysis enzyme, a plasminogen receptor and a DNA binding protein. ENO1 play an important role in the process of cancer development.
Alpha-enolase - Wikipedia
网页Enolase 1 (ENO1), more commonly known as alpha-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a …
Enolase - an overview | ScienceDirect Topics
网页Enolase (EC 4.2.1.11) is a cytosolic metalloenzyme responsible for the conversion of 2-phosphoglycerate into phosphoenolpyruvate, the second to last step in glycolysis. In mammals, enolase is encoded by three homologous genes.
Neuron-Specific Enolase as a Biomarker: Biochemical and Clinical ...
网页Neuron-specific enolase (NSE) is known to be a cell specific isoenzyme of the glycolytic enzyme enolase. In vertebrate organisms three isozymes of enolase, expressed by different genes, are present: enolase α is ubiquitous; enolase β is muscle-specific and enolase γ is neuron-specific.
Multifunctional roles of γ-enolase in the central nervous system: …
网页2024年5月12日 · Enolase, a multifunctional protein with diverse isoforms, has generally been recognized for its primary roles in glycolysis and gluconeogenesis. The shift in isoform expression from α-enolase to neuron-specific γ-enolase extends beyond its enzymatic role.
Enolase - an overview | ScienceDirect Topics
网页Enolase is a catalytic enzyme found mainly in cellular cytosol that is essential to fermentation as well as glucose catabolism and production. Its enzymatic properties were discovered in 1934 by Lohman and Meyerhof.
Beyond ENO1, emerging roles and targeting strategies of other …
网页Enolase is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate into phosphoenolpyruvate. In mammals, enolases exist in three isoforms, encoded by the genes ENO1, ENO2, and ENO3. The altered expression of enolases is a common occurrence in various types of cancer.
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