Topotecan - Wikipedia
网页Topotecan is a synthetic analog of camptothecin that inhibits topoisomerase I, an enzyme involved in DNA unwinding. It is used to treat ovarian, cervical and lung cancers, and is also being studied for other cancers and Angelman's syndrome.
Topotecan Hydrochloride - NCI - National Cancer Institute
网页Topotecan hydrochloride is a chemotherapy drug that damages the DNA of cancer cells and other rapidly growing cells, causing them to die. It is approved to treat cervical, ovarian, and small cell lung cancers, and is also being studied in other types of cancer.
Topotecan oral/injection Uses, Side Effects & Warnings - Drugs.com
网页2024年4月5日 · Topotecan is a chemotherapy drug used to treat ovarian, cervical, and lung cancers. It can cause serious side effects and harm an unborn baby or fertility. Learn how to use it, store it, and get medical advice.
托泊替康 - 百度百科
网页拓扑替康（Topotecan）为喜树碱半合成衍生物，是一种抑制拓扑异构酶Ⅰ的药物，能与拓扑异构酶Ⅰ-DNA复合物结合，从而阻碍断裂DNA单链的重新链接。 形成的拓扑替康-拓扑异构酶Ⅰ-DNA三元复合物与复制酶相互作用，造成双链DNA的损伤。
Topotecan: Uses, Interactions, Mechanism of Action - DrugBank …
网页Topotecan is an antineoplastic agent that inhibits DNA topoisomerase I and is used to treat ovarian, lung, and cervical cancers. Learn about its structure, pharmacology, pharmacokinetics, and adverse effects from DrugBank Online, a …
Topotecan: MedlinePlus Drug Information
网页Topotecan is a chemotherapy medication used to treat small cell lung cancer that has returned after initial treatment. It may cause serious infections, diarrhea, and other side effects. Learn how to use it safely and what precautions to follow.
Topotecan (Hycamtin) | Cancer information | Cancer Research UK
网页Topotecan is a chemotherapy drug for ovarian, lung and cervical cancers. It works by blocking a chemical that helps cells divide and repair DNA. Learn about its side effects, how to take it and when to contact your team.
托普樂肯 - 维基百科，自由的百科全书
网页托普樂肯 （Topotecan；商品名： Hycamtin ®， 癌康定）是一種化學治療藥物，為拓樸異構酶I抑制物，一般用來治療 卵巢癌 與 肺癌 等癌症。 给药方式. 为 静脉注射，不过有口服的研究。 副作用. 腹泻. 低 血细胞计数. 骨髓抑制. 容易受到 感染. 參見. NCI Drug Dictionary Definition of Topotecan （页面存档备份，存于 互联网档案馆） NCI Drug Information for Patients （页面存档备份，存于 互联网档案馆） 分类： . 拓扑异构酶抑制剂. 吡喃吲嗪喹 …
Topotecan - Memorial Sloan Kettering Cancer Center
网页Topotecan is a medication used to treat cancer. It can cause low blood cell counts, infections, bleeding, diarrhea, and lung problems. Learn how to take it, what to tell your doctor, and what to do in case of side effects.
Topotecan - A novel topoisomerase I inhibitor: pharmacology and ...
网页Topotecan, a water-soluble analogue of camptothecin, is a newly available cytotoxic agent which acts as an inhibitor of topoisomerase I, an enzyme necessary for DNA replication. Topotecan is a semisynthetic product derived from camptothecin, which was discovered during a National Cancer Institute cytotoxic drug screening program almost 30 years ...
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