Saponin - Wikipedia
网页The saponins are a subclass of terpenoids, the largest class of plant extracts. The amphipathic nature of saponins gives them activity as surfactants with potential ability to interact with cell membrane components, such as cholesterol and phospholipids, possibly making saponins useful for development of cosmetics and drugs. [7]
Saponin Synthesis and Function - PMC - National Center for ...
网页While membrane permeabilisation is a common feature of saponins, these compounds are also likely to have further effects on cells, for example, by interfering with cellular processes, such as enzyme activities, transport, organelle integrity, redox-related functions and other signal transduction processes and through triggering apoptosis (e.g ...
Saponin - an overview | ScienceDirect Topics
网页Saponins are plant-based natural glycosides of steroid or triterpene having the capacity to trigger mammalian immune system through stimulating both Th1 immunity and the production of cytotoxic T-lymphocytes (CTLs) thus making it a potential adjuvant for various vaccines in preclinical and clinical studies [86].
IF Protocol with Saponin Permeabilization | Cell Signaling Technology
网页Immunofluorescence Protocol with Saponin Permeabilization: easy to follow directions describing the step by step experimental procedure.
Metabolic and functional diversity of saponins, biosynthetic ...
网页2014年10月6日 · M. truncatula synthesizes a diverse array of saponins that can be classified into two main types, the hemolytic and non-hemolytic saponins, based on their ability to lyse red blood cells. Both types of saponin are synthesized through sequential oxidation and glycosylation of the oleanane aglycone, β-amyrin.
Saponin - an overview | ScienceDirect Topics
网页Abstract. Various saponins, plant glycosides with favorable anti-tumorigenic properties, have been used to inhibit tumor cell growth by cell cycle arrest and apoptosis with IC50 values of up to 0.2 μM.
Saponin Synthesis and Function - SpringerLink
网页2012年1月1日 · The biological activity of saponins is normally attributed to the amphipathic properties of these molecules, which consist of a hydrophobic triterpene or sterol backbone and a hydrophilic carbohydrate chain, although some saponins are known to have potent biological activities that are dependent on other aspects of their structure.
Dynamics of Cell Membrane Permeabilization by Saponins Using Terahertz ...
网页2020年8月18日 · Using attenuated total reflection in the terahertz domain, we studied the dynamics of Madine-Darby canine kidney cells after permeabilization by saponin molecules. We developed an analytical model taking into account saponin molecule diffusion, cell geometry, cytosol molecule diffusion, and pore dynamics.
(PDF) Saponins and their biological activities - ResearchGate
网页2009年3月1日 · Saponins are steroid or triterpenoid glycosides, common in a large number of plants and plant products that are important in human and animal nutrition. Several...
A review: structure–activity relationship between saponins
网页2022年12月30日 · The present study of the structure–activity relationship suggests that aglycones, glycochains on aglycones and special functional groups of saponins affect the immune activity of saponins. This paper reviews the effects of different saponins on cellular immunity. As well as the structure–activity relationship of saponins.