Lidocaine vs Procaine Comparison - Drugs.com
网页Compare Lidocaine vs Procaine head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
Local Anesthetics, Procaine, Lidocaine, and Mepivacaine Show ...
网页2017年12月11日 · In our study, the skin response of the ALA mepivacaine 1% was similar to that of procaine in erythema diameter and color intensity within the first 15 minutes. Lidocaine showed milder skin responses, more similar to those of NaCl.
Clinical use of local anesthetics in anesthesia - UpToDate
网页2024年4月26日 · Commonly used ester LAs include chloroprocaine, procaine, and tetracaine. The commonly used amide LAs include lidocaine, bupivacaine, ropivacaine, mepivacaine, and outside the United States, levobupivacaine. Articaine is an amide LA used primarily in dentistry. LAs are weak bases that exist in solution in both charged and uncharged forms.
Procaine - StatPearls - NCBI Bookshelf
网页2023年5月8日 · Historically, procaine has been used for local, regional, and neuraxial anesthesia via local infiltration, peripheral nerve blockade, and intrathecal injection. Since its development, however, newer local anesthetics such as lidocaine, bupivacaine, and mepivacaine have largely supplanted the use of procaine in everyday practice.
Clinical Pharmacology of Local Anesthetics - NYSORA
网页Procaine, the first synthetic ester LA, was introduced in 1904 by Einhorn. The introduction of the amide LA lidocaine in 1948 was transformative. Lidocaine quickly became used for all forms of regional anesthesia. Other amide LAs based on the lidocaine structure (prilocaine, etidocaine) subsequently appeared.
Essentials of Local Anesthetic Pharmacology - PMC - National …
网页2006年1月22日 · Procaine (Novocain) was introduced in 1905 and became the first local anesthetic to gain wide acceptance in the United States. However, its popularity declined after the introduction of lidocaine in 1948. Today, lidocaine is the most widely used agent, but all local anesthetics have comparable efficacy.
Lidocaine: The Origin of a Modern Local Anesthetic
网页The procaine in the wheal lasted 17 min, whereas 1% lidocaine lasted, on average, 70 min. A huge difference! It was so completely reliable that we thought statistical analysis was unnecessary.
Spinal anesthesia: a comparison of procaine and lidocaine
网页Purpose: To compare spinal procaine to spinal lidocaine with regard to their main clinical characteristics and incidence of transient radicular irritation (TRI). Methods: In this randomized, double-blind, prospective study, patients (two groups, n=30 each) received either 100 mg of lidocaine 5% in 7.5% glucose (Group L) or 100 mg of procaine 10 ...
Anesthesia: Numbed by choices - Harvard Health
网页2006年12月1日 · Now lidocaine has largely replaced procaine because it works faster and lasts longer. Unlike procaine, it's absorbed through the skin and is the active ingredient in topical agents. Local anesthesia. Lidocaine and other agents cause numbness by blocking ion channels in the membranes of nerve endings. Blocking pain.
Local/Topical Anesthetics: Local and Topical Anesthetics - Medscape
网页Amino esters include procaine, chloroprocaine, tetracaine, cocaine, and benzocaine. [1, 2, 3, 4, 5] Amino amides include dibucaine, lidocaine, mepivacaine, prilocaine, bupivacaine,...
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