The thymic stromal cell line MTSC4 induced thymocyte apoptosis …
网页2004年4月1日 · MTSC4 is a mouse thymic dendritic cell-like cell line established in our laboratory. It was identified by the expression of vimentin and S-100 protein and...
The thymic stromal cell line MTSC4 induced thymocyte apoptosis …
网页Mouse thymic stromal cell line 4 (MTSC4) is one of the stromal cell lines established in our laboratory. While losing the characteristics of epithelial cells, they express some surface markers shared with thymic dendritic cells (TDCs). To further study the biological functions of these cells, we com ….
In vitro enhancing effects of thymic dendritic cells on ... - PubMed
网页Using terminal deoxynucleotide transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) assay and propidium iodide-DNA staining flow cytometry assay, the effects of mouse thymic dendritic cells (MTSC4) on the process of programmed cell death of thymocytes in vitro were investigated.
The Thymic Stromal Cell Line MTSC4 Induced Thymocyte …
网页We found that MTSC4 selectively augmented the apoptosis of CD4+8+ (DP) thymocytes. This effect was Fas/FasL independent and could not be blocked by antibodies to MHC class I and class II molecules. In addition, MTSC4 enhanced the apoptosis of DP thymocytes from different strains of mice, which implies that MTSC4-induced thymocyte apoptosis is ...
The thymic stromal cell line MTSC4 induced thymocyte
网页2004年5月1日 · We found that MTSC4 selectively augmented the apoptosis of CD4+8+ (DP) thymocytes. This effect was Fas/FasL independent and could not be blocked by antibodies to MHC class I and class II...
Membrane molecules in induction of apoptosis of thymocytes
网页The DNA fragmentation of thymocytes induced by MTSC4 was inhibited by the addition of 20 mmol/L N-acetyl galactosamin monosaccharide and the pretreatment of a monoclonal antibody (PF-18-3) which recognized a putative antigen on MTSC4.
[Cytokine production by MTSC 4 cells, an established mouse
网页The cytokine production by MTSC 4 cells, a murine thymic dendritic cell line established in our laboratory, has been investigated. Without exogenous stimulation, the MTSC 4 cells constitutively produce multiple types of cytokines, including IL-1, IL-6, IL-7, CSF, IFN and Chemotactic factor (CF).
In vitro enhancing effects of thymic dendritic cells on apoptotic …
网页Using terminal deoxynucleotide transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) assay and propidium iodide-DNA staining flow cytometry assay, the effects of mouse thymic dendritic cells (MTSC4) on the process of programmed cell death of thymocytesin vitro were investigated.
The thymic stromal cell line MTSC4 induced thymocyte ... - Europe …
网页2004年4月1日 · Europe PMC is an archive of life sciences journal literature.
Capability of antigen presentation by mouse thymic stromal cells
网页2000年1月1日 · Apoptosis of thymocytes induced by MTSC4 and TDCs was measured by Annexin V and PI staining and analyzed by flow cytometry. We found that MTSC4 selectively augmented the apoptosis of CD4+8+ (DP...