Tetramethylpyrazine - Wikipedia
网页Tetramethylpyrazine, also known as ligustrazine, is a chemical compound found in nattō and in fermented cocoa beans. [1] In an observational study, tetramethylpyrazine was the dominant volatile organic compound in one sourdough starter. [2] When purified, tetramethylpyrazine is a colorless solid. It is classified as an alkylpyrazine.
川芎嗪 - 百度百科
网页舒张家兔血管，增强心肌收缩力，加快心率，降低压力感受器敏感性和兴奋交感神经中枢，使正常血压兔、去甲肾上腺上腺上腺素性急性高血压兔的血压降低，剂量依赖性增加肾血流量，并且有一定的利尿作用。. 4.改善脑循环川芎嗪对脑缺血再灌注所致脑损伤有 ...
Ligustrazine - SpringerLink
网页2018年11月20日 · Ligustrazine is an alkaloid derived from chuanxiong 川芎 (Ligusticum chuanxiong Hort; L. wallichii). Ligusticum wallichii Franchat (or Ligusticum chuanxiong Hort; L. wallichii), a member of the Umbelliferaceae family, is a Chinese medicinal herb that is a common constituent in polypharmaceutical herbal drugs.
Tetramethylpyrazine: A Review of Its Antitumor Potential and …
网页2021年12月16日 · Among them, the main alkaloid component is tetramethylpyrazine (TMP) (Figure 1), also known as ligustrazine (chemical name: 2,3,5,6-tetramethylpyrazine; pyrazine; molecular formula: C 8 H 12 N 2). TMP is an effective monomer obtained from the alkaloid of Chuanqiong and is also the main active substance in Chuanqiong.
Ligustrazine for the Treatment of Unstable Angina: A Meta …
网页2016年4月26日 · Ligustrazine is a principal ingredient of chuanxiong. It has been shown to play a critical role in cardiovascular treatments, mediated by inhibition of Ca 2+ influx and by the release of intracellular Ca 2+ [11, 12].
Meta-Analysis of Clinical Efficacy and Safety of Ligustrazine in the ...
网页2020年11月6日 · Ligustrazine has certain clinical efficacy in the treatment of IPF, but the safety of applying it and the adverse reactions need to be further analyzed and determined. It can be considered as a new alternative and complementary medicine to be promoted and recommended for use in medical units in vari ….
Efficacy of Ligustrazine Injection as Adjunctive Therapy in Treating ...
网页Ligustrazine injection has been widely used to treat ACI in China over the past decades, this famous Chinese medicine is completely unknown to most Western physicians and researchers. Therefore, this study aims to provide an internationally accessible systematic review for evaluating the effectiveness and safety of ligustrazine injection in the ...
Ligustrazine Alleviate Acute Lung Injury Through Suppressing …
网页2021年5月28日 · Ligustrazine (Tetramethylpyrazine, TMP) is an active substance extracted from the Umbelliferae plant Ligusticum chuanxiong. It has been proven to have antioxidant and inflammation effects. The study was designed to explore the efficacy and specific mechanism of TMP for ALI/ARDS treatment. Here, we c …
Meta-Analysis of the Clinical Effectiveness and Safety of Ligustrazine …
网页2016年9月21日 · Ligustrazine is a new type of calcium ion antagonist and free radical scavenger, which can pass through the blood brain barrier. High dose of ligustrazine can significantly enhance the expression of Bcl-2 and reduce the expression of p53 .
Meta‐Analysis of Clinical Efficacy and Safety of Ligustrazine in the ...
网页2020年11月6日 · Meta-analysis showed that Ligustrazine was more effective to medicine in improving clinical efficiency, improving pulmonary function (TLC %, VC %, DLCO %), and blood gas analysis (PaO 2, PaCO 2), suggesting that Ligustrazine was effective and feasible in treating IPF.
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