A Whole-Body Musculoskeletal Model of the Mouse - PMC
网页For ankle inversion, medial gastrocnemius has the highest moment-arm and moment among all the muscles in its group. Peroneus digiti quarti, peroneus longus, and peroneus brevis have large moment-arms for ankle abduction, while lateral gastrocnemius, flexor digitorum longus, and peroneus longus Can exert large moments for ankle abduction.
Metabolomic Analysis of Skeletal Muscle in Aged Mice
网页2019年7月18日 · Gastrocnemius muscles of 8-week-old male mice (N = 5, young group) and 28-month-old male mice (N = 5, aged group) were used for the metabolomic analysis (Human Metabolome Technologies Inc ...
Molecular and phenotypic analysis of rodent models reveals …
网页2021年2月12日 · Here we generated a time series of phenotypic measurements and RNA sequencing data in mouse gastrocnemius muscle and analyzed them alongside analogous data from rats and humans. We found that...
A non-invasive mouse model that recapitulates disuse-induced …
网页2023年12月14日 · In this study, we established new immobilization-atrophy mice model with minimal side effects and conducted RNAseq to analyze differentially expressed genes in mice gastrocnemius muscle at seven...
The C57Bl/6 mouse serves as a suitable model of human skeletal muscle ...
网页2012年11月23日 · Our first objective is to compare and contrast mitochondrial function across the lateral portion of mouse quadriceps (QUAD M), SOL M and lateral gastrocnemius (GAST M). Hitherto, differences in mitochondrial function across skeletal muscles have been attributed primarily to the differences in mitochondrial content ( Hoppeler et al. 1987 ...
Comparative analysis of mouse skeletal muscle fibre type …
网页2005年2月14日 · Myosin isoforms of mouse muscles were compared to those of rat gastrocnemius muscle (lane 1). Densitogram of each lane is shown above the gel. The muscles analysed were m. gastrocnemius (lane 2), m. …
Beneficial Effects of Resveratrol in Mouse Gastrocnemius: A Hint …
网页2021年9月15日 · Resveratrol treatment of mice exposed to a seven-day period of unloading prevented body and muscle weight and limb strength loss, while an improvement in muscle proteolysis, proteolytic markers, atrophy signaling pathways, apoptosis, and muscle fiber CSA was observed in the gastrocnemius muscle.
Dissection, in vivo imaging and analysis of the mouse ...
网页Muscles of the distal leg, for instance the gastrocnemius and tibialis anterior, are commonly used in such studies with mice and rats. However, thin and flat muscles, which can be dissected, processed and imaged without major disruption to muscle fibres and nerve-muscle contacts, are more suitable for accurate and detailed analyses of the ...
Assessment of muscle mass and strength in mice - PMC
网页2015年8月19日 · Remove the gastrocnemius (GSN), tibialis anterior (TA), extensor digitorum longus (EDL), soleus (SOL) and quadriceps muscles. Blot the muscles dry with filter paper and weigh the muscles on an analytical scale. Accuracy is extremely important, especially for small muscles, such as TA, EDL and SOL.
The C57Bl/6 mouse serves as a suitable model of human skeletal ... - PubMed
网页Mouse quadriceps (QUAD(M)), soleus (SOL(M)) and gastrocnemius (GAST(M)) skeletal muscles were obtained from 8- to 10-week-old healthy mice (n = 8), representing mixed, oxidative and glycolytic muscle, respectively. Skeletal muscle samples were also collected from young, active, healthy human subjects (n = 8) from the vastis lateralis (QUAD(H)).