Foam cell - Wikipedia
网页Foam cells, also called lipid-laden macrophages, are a type of cell that contain cholesterol. These can form a plaque that can lead to atherosclerosis and trigger myocardial infarction and stroke .
Macrophages and Foam Cells: Brief Overview of Their Role, …
网页2021年9月14日 · This overview is focusing on the role of macrophages in atherogenesis, which are at the same time a part of the inflammatory response, and also tightly linked to the foam cell formation, thus taking part in both crucial for atherogenesis processes.
Foam Cells in Atherosclerosis: Novel Insights Into Its Origins ...
网页2022年4月13日 · Foam cells play a vital role in the initiation and development of atherosclerosis. This review aims to summarize the novel insights into the origins, consequences, and molecular mechanisms of foam cells in atherosclerotic plaques.
Foam cells - Latest research and news | Nature
网页2024年8月26日 · Foam cells are a type of macrophage that localize to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a...
Foam Cells in Atherosclerosis: Novel Insights Into Its Origins ...
网页2022年4月13日 · Foam cells undergo diverse pathways of programmed cell death including apoptosis, autophagy, necroptosis, and pyroptosis, contributing to the necrotic cores of atherosclerotic plaques. The formation of foam cells is affected by cholesterol uptake, efflux, and esterification.
Foam cell formation: A new target for fighting atherosclerosis …
网页2019年1月1日 · The process of foam cell formation involves the expression of specific chemokine receptors and chemoattractant proteins (red) for monocyte extravasation; cytokines for macrophage differentiation and polarisation (blue), and lipid scavenger receptors (green) and transport carriers (orange) for cholesterol uptake and efflux.
Foam Cells as Therapeutic Targets in Atherosclerosis with a Focus …
网页2021年3月3日 · Since foam cells are a central player in the underlying pathology of atherosclerosis, reducing the formation of foam cells, or inducing their removal, might represent an effective therapeutic strategy. Recently, several groups reported that targeting foam cells could effectively ameliorate atherosclerosis, which are described in this review.
泡沫细胞 - 维基百科，自由的百科全书
网页泡沫细胞是导致 动脉硬化 的一种原因，并可能导致 心脏病 和 脑梗塞。 形成. 当 低密度脂蛋白 穿过 动脉 内膜进入血管壁之间时，胆固醇会在那里堆积。 [1] 当胆固醇堆积足够时，血管内膜的 内皮细胞 会释放 激素 招引 单核细胞，单核细胞进而分化为 巨噬细胞。 [2] 巨噬细胞吞噬了被自己产生的 自由基 氧化 的胆固醇并试图把脂肪 消化 掉。 在巨噬细胞中堆积的脂肪使细胞成为泡沫细胞。 参见. 动脉粥样硬化. 巨噬细胞. 参考文献.
Macrophages and Foam Cells: Brief Overview of Their Role
网页2021年9月14日 · This overview is focusing on the role of macrophages in atherogenesis, which are at the same time a part of the inflammatory response, and also tightly linked to the foam cell formation, thus taking part in both crucial for atherogenesis processes.
The macrophage foam cell as a target for therapeutic intervention …
网页2002年11月1日 · New approaches to inhibit lipid accumulation in macrophage foam cells and reduce inflammatory responses may be of therapeutic value in preventing coronary artery disease. Macrophages are...
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