FGL2 Gene - GeneCards | FGL2 Protein | FGL2 Antibody
网页2024年8月6日 · FGL2 is a protein coding gene that encodes a fibrinogen-like protein involved in mucosal immunity. Learn about its aliases, disorders, pathways, products, expression, localization, and more.
FGL2 protein expression summary - The Human Protein Atlas
网页Cell type enhanced (monocytes, Langerhans cells, Kupffer cells, Macrophages, Schwann cells) Single cell type expression cluster i
Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical ...
网页2020年7月27日 · Furthermore, the expression level of FGL2 was positively correlated with the immune cell infiltrations in breast cancer, especially those cells with high antitumor activities. GO, KEGG, and GSEA analyses also validated that FGL2 was closely related to genes involved in the immune response, signal transduction, and T cell receptor signaling ...
Fibrinogen-like protein 2 in inflammatory diseases: A future ...
网页2023年3月1日 · FGL2 shows complex properties in inflammatory diseases. mFGL2 can initiate coagulation in tissue by serine protease activity, resulting in fibrin deposition, which has been demonstrated in viral hepatitis, IBD, and sepsis. sFGL2 can suppress T-cell proliferation, inhibit DC maturation, induce B-cell apoptosis, inhibit …
Characterization of fibrinogen-like protein 2 (FGL2): Monomeric FGL2 …
网页2013年2月1日 · Fibrinogen-like protein 2 (FGL2), a novel effector molecule of CD4 + CD25 + Foxp3 + regulatory T cells (Treg), mediates its suppressive activity through binding to low affinity Fcγ receptors expressed on antigen presenting cells (APCs). FGL2 has been implicated in the pathogenesis of viral hepatitis, xeno- and allotransplant rejection, and ...
Fibrinogen-like protein 2: Its biological function across cell types ...
网页2023年2月1日 · Fibrinogen-like protein 2 (FGL2), which induces transformation from low-grade glioma to high-grade glioblastoma, is a type II membrane protein that is highly expressed in both host immune cells and tumor cells.
Targeted Deletion of fgl2 Leads to Impaired Regulatory T Cell …
网页2008年1月1日 · Mice with targeted deletion of fibrinogen-like protein 2 (fgl2) spontaneously developed autoimmune glomerulonephritis with increasing age, as did wild-type recipients reconstituted with fgl2 −/− bone marrow.
Immune cell - FGL2 - The Human Protein Atlas
网页Immune cell type specificity: Group enriched (non-classical monocyte, intermediate monocyte, neutrophil, classical monocyte, eosinophil, myeloid DC) Monaco dataset i The …
Optogenetic stimulation promotes Schwann cell proliferation ...
网页2019年3月5日 · Schwann cells (SCs) constitute a crucial element of the peripheral nervous system, by structurally supporting the formation of myelin and conveying vital trophic factors to the nervous system....
FGL2 promotes tumor progression in the CNS by suppressing CD103
网页2019年1月25日 · Here, the authors show that FGL-2 expressed by GBM cancer cells acts by suppressing the differentiation of CD103+ DC cells required to activate the anti-tumor CD8+ T cell response via...
- 某些结果已被删除