Desmoplasia - Wikipedia
网页Desmoplastic small round cell tumour, with desmoplasia surrounding nests of cancer cells. In medicine, desmoplasia is the growth of fibrous connective tissue. [1] It is also called a desmoplastic reaction to emphasize that it is secondary to an insult.
Desmoplastic Small Round Cell Tumors (DSRCT) - NCI
网页Desmoplastic Small Round Cell Tumors (DSRCT) are tumors that grow in the abdomen and pelvic area of the body. DSRCT is very rare and most commonly occurs in white males between the ages of 10 and 30 years old. Learn more about how this cancer forms, is treated, and the prognosis.
Desmoplastic small round cell tumors - Symptoms and causes
网页2024年2月23日 · Desmoplastic small round cell tumors are rare cancers that begin as a growth of cells. The growths often form on the tissue that lines the inside of the abdomen and pelvis. This tissue lining is called the peritoneum.
Desmoplastic Melanoma: A Review - PMC - National Center for ...
网页Desmoplastic melanoma (DM) is a variant of spindle cell melanoma typically found on chronically sun-damaged skin of older individuals. Early diagnosis can be challenging because it is often amelanotic and has a predominantly dermal component.
Desmoplastic Small Round Cell Tumors - MD Anderson Cancer Center
网页Desmoplastic small round cell tumors (DSRCT) are a type of soft-tissue sarcoma. DSRCT causes multiple tumors to form in the abdomen and pelvis area, but exactly where it begins usually is not known. The first case of a DSRCT was recorded in 1989, and about 200 cases have been diagnosed since then.
Desmoplastic stroma restricts T cell extravasation and ... - Nature
网页2023年8月22日 · The desmoplastic stroma in solid tumors presents a formidable challenge to immunotherapies that rely on endogenous or adoptively transferred T cells, however, the mechanisms are poorly...
Significance of desmoplastic reactions on tumor deposits in …
网页2022年11月8日 · The desmoplastic reaction (DR) is a fibrous tissue reaction around tumor cells, and the prognostic significance of DR in colorectal cancer (CRC) has been established. Tumor deposits (TD) are also an important prognostic indicator of CRC. Notably, immature type DR has been linked to poor prognosis.
Desmoplasia - SpringerLink
网页2017年1月1日 · Activated fibroblasts expand and contribute to an increased stromal response known as desmoplasia. Desmoplasia can be associated with increased tumor stage and poor prognosis in breast cancer patients, but it is unclear whether fibroblasts are active inducers or passive participants in cancer progression.
Multifaced roles of desmoplastic reaction and fibrosis in …
网页2023年7月21日 · Desmoplastic reaction is a type of fibrotic response initiated by tissue injury or inflammation. It is characterized by ECM component accumulation, including collagen and fibronectin, and an increase in myofibroblast number and activity.
Pembrolizumab Alone to Treat Desmoplastic Melanoma
网页2023年5月5日 · People with desmoplastic melanoma, a rare form of skin cancer, are likely to benefit from treatment with a single immunotherapy drug, pembrolizumab (Keytruda), new results from a small clinical trial suggest.
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