Mpox - World Health Organization (WHO)
网页2024年8月26日 · Mpox, previously known as monkeypox, is a viral illness caused by the monkeypox virus, a species of the genus Orthopoxvirus. There are two distinct clades of the virus: clade I (with subclades Ia and Ib) and clade II (with subclades IIa and IIb). In 2022–2023 a global outbreak of mpox was caused by the clade IIb strain.
网页2024年8月21日 · While clades I and II mpox viruses are genetically similar enough that vaccines and treatments are expected to be effective, it is not well understood how prior infection with clade IIb (responsible for the ongoing global outbreak) or vaccination might protect from infection with or complications from clade I. CDC recommends that all ...
Mpox is spreading rapidly. Here are the questions researchers are ...
网页2024年8月28日 · The Democratic Republic of the Congo (DRC) has spent decades grappling with monkeypox clade I virus — the lineage to which Ib belongs. But in the past, clade I infections usually arose when a...
FACT SHEET: United States Response to the Clade I Mpox …
网页2024年8月22日 · In 2022, the world experienced a global outbreak of clade IIb mpox, which led to more than 95,000 cases across 115 non-endemic countries and continues to occur in the United States. The Biden-Harris Administration responded by ensuring the JYNNEOS mpox vaccine was available to at-risk populations in the U.S.
Broad protection against clade 1 sarbecoviruses after a single
网页2024年2月12日 · Here, the authors designed a trivalent spike-protein-nanoparticle vaccine that elicits neutralizing antibodies and protects female hamsters against challenges with SARS-CoV-2-like and SARS-CoV-1...
WHO declares mpox virus a public health emergency of …
网页2024年8月14日 · Clade 1 has been circulating in the DRC for years while clade 2 was responsible for the global outbreak of 2022 which was declared an international public health emergency. Tedros said in the...
网页2024年6月10日 · The Democratic Republic of Congo (DRC) mpox outbreak is now reporting the largest surge in clade I mpox cases ever recorded in the country. As of May 30, 2024, CDC reports DRC has recorded more than 20,000 confirmed and suspected cases and more than 1,000 deaths in the current outbreak.3.
网页2024年7月12日 · While experts believe that the clade I outbreak is currently contained to the DRC, health nuary 1, 2023 to April 14, 2024. Additionally, 67% of all cases and 78% of deaths have occurred among ch
Clade I Mpox Outbreak Originating in Central Africa
网页Clade I mpox occurs regularly, or is endemic, in DRC. The current outbreak is more widespread than any previous DRC outbreak, and clade I mpox has spread to some neighboring countries, including Burundi, Central African Republic, Republic of the Congo, Rwanda, Uganda, and a travel-associated case in Kenya.
Sustained human outbreak of a new MPXV clade I lineage in
网页2024年6月13日 · Two distinct genetic MPXV clades exist: clade I mainly in Central Africa, especially the Democratic Republic of the Congo (DRC), and is associated with severe clinical symptoms and substantial...