Adenylylation - Wikipedia
网页Adenylylation involves a phosphodiester bond between a hydroxyl group of the molecule undergoing adenylylation, and the phosphate group of the adenosine monophosphate nucleotide (i.e. adenylic acid). Enzymes that are capable of catalyzing this process are called AMPylators.
腺苷酸环化酶 - 维基百科，自由的百科全书
网页腺苷酸环化酶 （adenylate cyclase，adenyl cyclase，adenylyl cyclase，缩写 AC）， EC 4.6.1.1，系统名称为 ATP二磷酸裂解酶，是一种参与已知所有 细胞调控 的关键酶，位于 细胞膜 内侧 [2]。. 其催化以下反应：. 腺苷三磷酸（ATP） = 3'，5'–环 腺苷一磷酸 …
Adenylyl cyclase - Wikipedia
网页Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase (cyclizing; 3′,5′-cyclic-AMP-forming). It catalyzes the following reaction: ATP = 3′,5′-cyclic AMP + diphosphate. It has key regulatory roles in essentially all cells. [2]
Adenylyl Cyclases - Basic Neurochemistry - NCBI Bookshelf
网页Regulation of cAMP formation by neurotransmitter receptors and intracellular messenger pathways is determined by the activity of the synthetic enzyme adenylyl cyclase, also termed adenylate cyclase. Adenylyl cyclase can be activated directly by forskolin, a plant diterpene which has been useful in studies of enzyme regulation and purification.
Structure and function of adenylyl cyclases, key enzymes in …
网页2020年8月1日 · Adenylyl cyclases (ACs) are the enzymes that generate cAMP, and thus the key components of the cAMP signaling and regulation pathways. In this review we provide a brief general overview of the field, focusing on the recent breakthroughs in our understanding of the structure and function of the ACs …
Targeting adenylate-forming enzymes with designed ... - Nature
网页2019年4月15日 · Adenylate-forming enzymes are a mechanistic superfamily that are involved in diverse biochemical pathways. They catalyze ATP-dependent activation of carboxylic acid substrates as reactive acyl...
腺苷酸環化酶 - 維基百科，自由的百科全書
网页腺苷酸環化酶（ adenylate cyclase ，adenyl cyclase，adenylyl cyclase，縮寫AC），EC 4.6.1.1，系統名稱為 ATP二磷酸裂解酶，是一種參與已知所有細胞調控的關鍵酶，位於細胞膜內側 [2] 。其催化以下反應：
Adenylate Kinase and AMP Signaling Networks: Metabolic …
网页2009年4月17日 · Adenylate kinase generated AMP is emerging as a potential metabolic signal whose intracellular and circulatory levels determine the balance of peripheral organ energy supply between glucose, glycogen and fat, thus regulating food intake, hormonal state, sleep, hibernation and body energy sensing in …
Adenylate-forming enzymes - PMC - National Center for …
网页Adenylation is an elegant biological process used to chemically activate carboxylate substrates by condensing them with ATP to liberate pyrophosphate (the driving force). The resulting carboxylate adenylate is very reactive and would be expected to …
Adenylate Definition & Meaning - Merriam-Webster
网页1991年6月21日 · ˌa-də-ˈni-lət, -ˌlāt. : a salt of adenylic acid. The catalytic activity involves the specific recognition of three substrates: the amino acid and ATP for the formation of an …
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